ea0070aep620 | Pituitary and Neuroendocrinology | ECE2020
Damasio Ines
, Cavaco Daniela
, Maciel Joana
, Dias Daniela
, Donato Sara
, Pinheiro Sara
, Figueiredo Ana
, Simões-Pereira Joana
, Pereira Conceiçao
Introduction: The combination of chemotherapy with prophylatic cranial radiotherapy (C-RT) allowed the improvement of survival rates of pediatric acute lymphoblastic leukemia (ALL) survivors while putting them at risk of develeping long-term endocrine deficiencies, like growth hormone deficiency (GHD).Current evidence suggests that the prevalence of GHD in children treated with radiation doses ≥ 30–50 Gy for non-pituitary brain tumors is...